"The New Frontier of RNA Nanotherapeutics" presented by the George and Angelina Kostas Research Center for Cardiovascular Nanomedicine

Houston, TX US
October 24, 2022

LIVE (In-Person) and LIVESTREAM (Virtual) attendance options are available.

Presented by the George and Angelina Kostas Research Center for Cardiovascular Nanomedicine

Program Directors: John P. Cooke, MD, PhD and Alessandro Grattoni, PhD

The RNA vaccines against COVID-19 mark the beginning of a technological revolution that will transform the way we treat disease and restore health. “The New Frontier of RNA Nanotherapeutics” annual international meeting, presented by the George and Angelina Kostas Research Center for Cardiovascular Nanomedicine, will feature a discussion on the events that led to the RNA vaccine breakthrough, and preview emerging RNA Nanotherapeutics. Advances in the design of RNA constructs to improve stability and translational efficiency, will be presented along with the leading-edge developments in nanomedicine to improve delivery and tissue specificity. The potential of nanotechnology-enabled RNA therapeutics to enhance health is virtually limitless. Join us in this international meeting at the frontiers of RNA Nanotherapeutics!


 Registration Type Fee
 Houston Methodist employee (in-person) Free
 All Others (in-person) $25
 Livestream (virtual attendance) Free


Poster abstracts are being solicited that address challenges in the field of cardiovascular nanomedicine. Prizes for the best poster presentations will be awarded at the Annual International Meeting. Click below for additional overview, guidelines and eligibility information.

Poster Submission Details

PDF icon Poster Abstract Submission Form.pdf

Poster Abstract Submission Deadline: 12 Noon CST, September 23, 2022
Poster Draft Submission Deadline: 12 Noon CST, October 10, 2022

SHARK TANK Cardiovascular Nanomedicine Competition
During the “Shark Tank” Cardiovascular Nanomedicine competition, three research teams will compete for a $10,000 award to fund innovative ideas in the field of cardiovascular nanomedicine. Each team will be given 5 minutes to virtually present their research project, and the judges will be provided 10 minutes to ask questions and discuss the work. The judges (Sharks) will vote on the winning project deemed to be the most likely to be translated toward the clinic. The best projects are based upon innovative ideas that solve a cardiovascular problem, and have preliminary data showing feasibility, combined with a target product profile and a plan for clinical development. The winning team will be announced at the conclusion of the competition.

Shark Tank Competition details

Letter of Intent (LOI) submission deadline: September 2, 2022.
LOI must be sent in PDF form to: events@houstonmethodist.org


Please visit our YouTube channel for videos from past Kostas meetings.

Target Audience

Scientists, physicians, nurses, researchers, residents/fellows, other health care professionals (surgery, cardiovascular, nanomedicine) will benefit from this course.

Course summary
Course opens: 
Course expires: 
Event starts: 
10/24/2022 - 9:00am CDT
Event ends: 
10/24/2022 - 5:30pm CDT

October 24, 2022

8:00 AMRegistration & Breakfast 
8:30 AMWelcome H. Dirk Sostman, MD, FACR, Houston Methodist
8:40 AM"The Limitless Future of RNA Nanotherapeutics: Its Promise for Cardiovascular Disease"John Cooke, MD, PhD, Houston Methodist
9:00 AM“Re-examining dogmas of RNA regulation to reveal new therapeutic strategies”Jeremy E. Wilusz, PhD, Baylor College of Medicine
9:30 AM

SMRTs* way to fix the heart
* Specific modified mRNA translation system

Lior Zangi, PhD, Mount Sinai
10:00 AM"An RNA Therapeutic to Reverse Aging"Vittorio Sebastiano, PhD, Stanford University
10:30 AM"Next Gen Lipid Nanoparticles for RNA Delivery"Prof. Dan Peer, Tel Aviv University
11:00 AM"Engineering RNA Carriers and RNA-Encoded Gene Circuit Regulators"Patrick S. Stayton, PhD, University of Washington
11:30 AMLightning Round Talks (2-minute blitz talks) Session chair: Alessandro Grattoni, PhD, Houston Methodist
12:00 PM

Lunch break & Poster Session

1:45 PMPanel Discussion & PresentationsSession Chair: John Cooke, MD, PhD, Houston Methodist
 Topic: The New Frontier of RNA NanotherapeuticsPanelists: 
  • Lior Zangi, PhD, Mount Sinai
  • Vittorio Sebastiano, PhD, Stanford University
  • Prof. Dan Peer, Tel Aviv University
  • Patrick S. Stayton, PhD, University of Washington
  • Biana Godin, PhD, Houston Methodist
  • Francesca Taraballi, PhD, Houston Methodist
  • Alessandro Grattoni, PhD, Houston Methodist
2:30 PMKeynote Speaker 
3:00 PM

“In vivo Delivery Systems for RNA and Genome Editing Tools”

Prof. Daniel G. Anderson, PhD, Massachusetts Institute of Technology
3:30 PM"RNA Nanoparticles for Cardiovascular Regeneration"Francesca Taraballi, PhD, Houston Methodist
3:50 PM"RNA Nanotherapeutic for skin regeneration"Biana Godin, PhD, Houston Methodist 
4:10 pmBreak 
4:15 PMShark Tank inspired session: Cardiovascular Nanomedicine Edition 
5:15 PMAwards AnnouncementJohn Cooke, MD, PhD, Houston Methodist
  • Poster Awards: (3) $250; (2) $750; (1) $1000
  • Shark Tank Award $10,000
  • Kostas Grant Award
5:25 PMClosing Remarks and AdjournmentJohn Cooke, MD, PhD, Houston Methodist


LIVE (in-person) and LIVESTREAM (virtual) attendance options are available.
Houston Methodist Research Institute
6670 Bertner, 2nd Floor, John F. Bookout Auditorium (R2-306)
Houston, TX 77030
United States

Program Directors

John P. Cooke, MD, PhD
Joseph C. Walter and Carole Walter Looke Presidential Distinguished Chair
Professor and Chair, Department of Cardiovascular Sciences
Director, Center for Cardiovascular Regeneration
Medical Director, Center for RNA Therapeutics
Chief Translational Officer, Houston Methodist Academic Institute

Alessandro Grattoni, PhD
Frank J. and Jean Raymond Centennial Chair
Chairman and Professor, Department of Nanomedicine 
Professor, Departments of Surgery & Radiation Oncology 

Houston Methodist Academic Institute


Prof. Daniel G. Anderson, PhD
Department of Chemical Engineering
Institute for Medical Engineering and Science
Harvard-MIT Division of Health Sciences & Technology
David H. Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology

Biana Godin, MScPharm, PhD
Assistant Professor of Nanomedicine, Academic Institute
Houston Methodist

Prof. Dan Peer 
Vice President for Research and Development
Director, Laboratory of Precision NanoMedicine 
Managing Director, SPARK Tel Aviv, Center for Translational Medicine
Tel Aviv University

Vittorio Sebastiano, PhD
Associate Professor, Department of Obstetrics and Gynecology
Stanford University

Patrick S. Stayton, PhD
Distinguished Career Professor
Department of Bioengineering
University of Washington

Francesca Taraballi, PhD
Assistant Professor of Orthopedic Surgery, Academic Institute
Director, Center for Musculoskeletal Regeneration
Houston Methodist

Lior Zangi, PhD
Associate Professor in the Department of Cardiology
Associate Professor, Department of Genetics and Genomic Science
Cardiovascular Research Institute (CVRI)
The Black Family Stem Cell Institute
Icahn School of Medicine at Mount Sinai
Hess Center for Science and Medicine

Jeremy E. Wilusz, PhD
Ruth McLean Bowman Bowers Professor
Associate Professor, Department of Biochemistry & Molecular Biology
Therapeutic Innovation Center (THINC)
Baylor College of Medicine

Exhibitor information coming soon...


Please login or register to take this course.


 Registration Type Fee
 Houston Methodist employee (in-person) Complimentary
 All Others (in-person) $25
 Livestream (virtual attendance) Complimentary


COVID-19 Disclaimer: The format of these activities is subject to change due to extenuating circumstances resulting from the COVID-19 pandemic. Should any activity be cancelled or changed to a new format (i.e., virtual only), Houston Methodist may cancel or modify your registration accordingly. We will make every effort to notify you of a change of format and your registration status before the activity date. Thank you for your understanding.